Skin surface lipids photo‐oxidation: A vibrational spectroscopy study

Skin surface lipid (SSL) film is a mixture of sebum and epidermal lipids protecting the skin from effects environment such as solar radiation. SSLs are suitable target scavenger for all reactive oxygen species (ROS) generated in skin. In SSLs, vitamin E has been identified one main antioxidants that can capture ROS. This paper third part global study evaluates effect radiation on classes constitute SSLs. first two parts, fatty acids triglycerides was studied using vibrational spectroscopy. this part, other squalene (SQ), cholesterol (Chol), wax ester (WE) (Palmitoleyl Palmitate) then behavior under monitored. Finally, were irradiated analyzed spectroscopy HT-GC/MS to respectively follow oxidation process identify When alone, SQ detectable only after 2430 J/cm2 dose. Similar observations obtained (after 1620 J/cm2). No changes observed Palmitate). contrast, when extracted human irradiated, more marked modifications SQ. confirmed antioxidant role by scavenging free radicals polyunsaturated (PUFA).